Combined Casein Kinase II inhibition and epigenetic modulation in acute B-lymphoblastic leukemia

BACKGROUND: The tumor suppressor protein phosphatase and tensin homolog (PTEN) is a key regulator of the PI3K/AKT pathway which is frequently altered in a variety of tumors including a subset of acute B-lymphoblastic leukemias (B-ALL). While PTEN mutations and deletions are rare in B-ALL, promoter h...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Richter, Anna, Roolf, Catrin, Hamed, Mohamed, Gladbach, Yvonne Saara, Sender, Sina, Konkolefski, Christoph, Knübel, Gudrun, Sekora, Anett, Fuellen, Georg, Vollmar, Brigitte, Murua Escobar, Hugo, Junghanss, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404304/
https://ncbi.nlm.nih.gov/pubmed/30841886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5411-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados