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Helios(+) and Helios(−) Treg subpopulations are phenotypically and functionally distinct and express dissimilar TCR repertoires
The transcription factor Helios is expressed in a large subset of Foxp3(+) Tregs. We previously proposed that Helios is a marker of thymic derived Treg (tTreg), while Helios(−) Treg were induced from Foxp3(−) T conventional (Tconv) cells in the periphery (pTreg). To compare the two Treg subpopulatio...
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| Izdano u: | Eur J Immunol |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6402968/ https://ncbi.nlm.nih.gov/pubmed/30620397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201847935 |
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