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Prognostic Impact of Immunohistochemical p53 Expression in Bone Marrow Biopsy in Higher Risk MDS: a Pilot Study

BACKGROUND AND OBJECTIVES: Mutations of the TP53 gene have an unfavorable prognosis in Myelodysplastic Syndromes (MDS). The product of the TP53 gene is the p53 protein. Most of the TP53 mutations entail the accumulation of the protein in the nucleus of tumor cells. The immunohistochemical (IHC) stai...

詳細記述

保存先:
書誌詳細
出版年:Mediterr J Hematol Infect Dis
主要な著者: Molteni, Alfredo, Ravano, Emanuele, Riva, Marta, Nichelatti, Michele, Bandiera, Laura, Crucitti, Lara, Truini, Mauro, Cairoli, Roberto
フォーマット: Artigo
言語:Inglês
出版事項: Università Cattolica del Sacro Cuore 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402551/
https://ncbi.nlm.nih.gov/pubmed/30858953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4084/MJHID.2019.015
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