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Prognostic Impact of Immunohistochemical p53 Expression in Bone Marrow Biopsy in Higher Risk MDS: a Pilot Study
BACKGROUND AND OBJECTIVES: Mutations of the TP53 gene have an unfavorable prognosis in Myelodysplastic Syndromes (MDS). The product of the TP53 gene is the p53 protein. Most of the TP53 mutations entail the accumulation of the protein in the nucleus of tumor cells. The immunohistochemical (IHC) stai...
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| Veröffentlicht in: | Mediterr J Hematol Infect Dis |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Università Cattolica del Sacro Cuore
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6402551/ https://ncbi.nlm.nih.gov/pubmed/30858953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4084/MJHID.2019.015 |
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