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Immune Checkpoint B7x (B7-H4/B7S1/VTCN1) is Over Expressed in Spontaneous Canine Bladder Cancer: The First Report and its Implications in a Preclinical Model

BACKGROUND: B7x (B7-H4/B7S1/VTCN1), an inhibitory immune checkpoint molecule is a potential therapeutic target owing to its immunosuppressive effect and well-known expression in cancers. Immune checkpoints in canine bladder cancer are largely undefined. Here, we report the first evaluation on expres...

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Bibliografiske detaljer
Udgivet i:Bladder Cancer
Main Authors: Chand, Damini, Dhawan, Deepika, Sankin, Alexander, Ren, Xiaoxin, Lin, Juan, Schoenberg, Mark, Knapp, Deborah W., Zang, Xingxing
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401562/
https://ncbi.nlm.nih.gov/pubmed/30854414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/BLC-180204
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