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The B7x Immune Checkpoint Pathway: From Discovery to Clinical Trial
B7x (B7-H4, B7S1, VTCN1) was discovered by us and others in 2003 as the seventh member of the B7 family. It is an inhibitory immune checkpoint with great significance to human diseases. Tissue-expressed B7x minimizes autoimmune and inflammatory responses. It is overexpressed in a broad spectrum of h...
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| Publicado no: | Trends Pharmacol Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6907741/ https://ncbi.nlm.nih.gov/pubmed/31677920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2019.09.008 |
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