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Viral Replicative Capacity, Antigen Availability via Hematogenous Spread, and High T(FH):T(FR) Ratios Drive Induction of Potent Neutralizing Antibody Responses

Live viral vaccines elicit protective, long-lived humoral immunity, but the underlying mechanisms through which this occurs are not fully elucidated. Generation of affinity matured, long-lived protective antibody responses involve close interactions between T follicular helper (T(FH)) cells, germina...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Eldi, Preethi, Chaudhri, Geeta, Nutt, Stephen L., Newsome, Timothy P., Karupiah, Gunasegaran
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401457/
https://ncbi.nlm.nih.gov/pubmed/30626686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01795-18
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