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Viral Replicative Capacity, Antigen Availability via Hematogenous Spread, and High T(FH):T(FR) Ratios Drive Induction of Potent Neutralizing Antibody Responses
Live viral vaccines elicit protective, long-lived humoral immunity, but the underlying mechanisms through which this occurs are not fully elucidated. Generation of affinity matured, long-lived protective antibody responses involve close interactions between T follicular helper (T(FH)) cells, germina...
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| Udgivet i: | J Virol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6401457/ https://ncbi.nlm.nih.gov/pubmed/30626686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01795-18 |
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