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Viral Replicative Capacity, Antigen Availability via Hematogenous Spread, and High T(FH):T(FR) Ratios Drive Induction of Potent Neutralizing Antibody Responses
Live viral vaccines elicit protective, long-lived humoral immunity, but the underlying mechanisms through which this occurs are not fully elucidated. Generation of affinity matured, long-lived protective antibody responses involve close interactions between T follicular helper (T(FH)) cells, germina...
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| 出版年: | J Virol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6401457/ https://ncbi.nlm.nih.gov/pubmed/30626686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01795-18 |
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