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Deficiency in Th2 Cytokine Responses Exacerbate Orthopoxvirus Infection

Ectromelia virus (ECTV) causes mousepox in mice, a disease very similar to smallpox in humans. ECTV and variola virus (VARV), the agent of smallpox, are closely related orthopoxviruses. Mousepox is an excellent small animal model to study the genetic and immunologic basis for resistance and suscepti...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sakala, Isaac G., Chaudhri, Geeta, Eldi, Preethi, Buller, R. Mark, Karupiah, Gunasegaran
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353717/
https://ncbi.nlm.nih.gov/pubmed/25751266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118685
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