TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection

Transmembrane serine protease TMPRSS2 activates the spike protein of highly pathogenic human coronaviruses such as severe acute respiratory syndrome-related coronavirus (SARS-CoV) and Middle East respiratory syndrome-related coronavirus (MERS-CoV). In vitro, activation induces virus-cell membrane fu...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Iwata-Yoshikawa, Naoko, Okamura, Tadashi, Shimizu, Yukiko, Hasegawa, Hideki, Takeda, Makoto, Nagata, Noriyo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401451/
https://ncbi.nlm.nih.gov/pubmed/30626688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01815-18
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