Participation of both Host and Virus Factors in Induction of Severe Acute Respiratory Syndrome (SARS) in F344 Rats Infected with SARS Coronavirus

To understand the pathogenesis and develop an animal model of severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV), the Frankfurt 1 SARS-CoV isolate was passaged serially in young F344 rats. Young rats were susceptible to SARS-CoV but cleared the virus rapidly within 3 to 5 day...

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Detalhes bibliográficos
Main Authors: Nagata, Noriyo, Iwata, Naoko, Hasegawa, Hideki, Fukushi, Shuetsu, Yokoyama, Masaru, Harashima, Ayako, Sato, Yuko, Saijo, Masayuki, Morikawa, Shigeru, Sata, Tetsutaro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797583/
https://ncbi.nlm.nih.gov/pubmed/17151094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01967-06
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