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Participation of both Host and Virus Factors in Induction of Severe Acute Respiratory Syndrome (SARS) in F344 Rats Infected with SARS Coronavirus

To understand the pathogenesis and develop an animal model of severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV), the Frankfurt 1 SARS-CoV isolate was passaged serially in young F344 rats. Young rats were susceptible to SARS-CoV but cleared the virus rapidly within 3 to 5 day...

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Bibliographische Detailangaben
Hauptverfasser: Nagata, Noriyo, Iwata, Naoko, Hasegawa, Hideki, Fukushi, Shuetsu, Yokoyama, Masaru, Harashima, Ayako, Sato, Yuko, Saijo, Masayuki, Morikawa, Shigeru, Sata, Tetsutaro
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797583/
https://ncbi.nlm.nih.gov/pubmed/17151094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01967-06
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