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Principles of resistance to targeted cancer therapy: lessons from basic and translational cancer biology

Identifying the genomic drivers of cancer has led to the clinical development of targeted therapies that strike at the heart of many malignancies. Nonetheless, many cancers outsmart such precision medicine efforts, and thus therapeutic resistance significantly contributes to cancer mortality. Attemp...

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Detalles Bibliográficos
Publicado en:Trends Mol Med
Main Authors: Sabnis, Amit J., Bivona, Trever G.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401263/
https://ncbi.nlm.nih.gov/pubmed/30686761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2018.12.009
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