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Principles of resistance to targeted cancer therapy: lessons from basic and translational cancer biology

Identifying the genomic drivers of cancer has led to the clinical development of targeted therapies that strike at the heart of many malignancies. Nonetheless, many cancers outsmart such precision medicine efforts, and thus therapeutic resistance significantly contributes to cancer mortality. Attemp...

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Detalhes bibliográficos
Publicado no:Trends Mol Med
Main Authors: Sabnis, Amit J., Bivona, Trever G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401263/
https://ncbi.nlm.nih.gov/pubmed/30686761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2018.12.009
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