L-arginine synthesis from L-citrulline in myeloid cells drives host defense against mycobacteria in vivo

Immunonutrition as a therapeutic approach is rapidly gaining interest in the fight against infection. Targeting L-arginine metabolism is intriguing, considering this amino acid is the substrate for antimicrobial nitric oxide production by macrophages. The importance of L-arginine during infection is...

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Veröffentlicht in:J Immunol
Hauptverfasser: Lange, Shannon M., McKell, Melanie C., Schmidt, Stephanie M., Zhao, Junfang, Crowther, Rebecca R., Green, Lisa C., Bricker, Rebecca L., Arnett, Eusondia, Köhler, S. Eleonore, Schlesinger, Larry S., Setchell, Kenneth D. R., Qualls, Joseph E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401247/
https://ncbi.nlm.nih.gov/pubmed/30710047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801569
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