L-arginine synthesis from L-citrulline in myeloid cells drives host defense against mycobacteria in vivo

Immunonutrition as a therapeutic approach is rapidly gaining interest in the fight against infection. Targeting L-arginine metabolism is intriguing, considering this amino acid is the substrate for antimicrobial nitric oxide production by macrophages. The importance of L-arginine during infection is...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Lange, Shannon M., McKell, Melanie C., Schmidt, Stephanie M., Zhao, Junfang, Crowther, Rebecca R., Green, Lisa C., Bricker, Rebecca L., Arnett, Eusondia, Köhler, S. Eleonore, Schlesinger, Larry S., Setchell, Kenneth D. R., Qualls, Joseph E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401247/
https://ncbi.nlm.nih.gov/pubmed/30710047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801569
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