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Unexpected genomic rearrangements at targeted loci associated with CRISPR/Cas9-mediated knock-in
The CRISPR/Cas9 gene editing tool enables accessible and efficient modifications which (re)ignited molecular research in certain species. However, targeted integration of large DNA fragments using CRISPR/Cas9 can still be challenging in numerous models. To systematically compare CRISPR/Cas9’s effici...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6401152/ https://ncbi.nlm.nih.gov/pubmed/30837594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40181-w |
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