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Application of Locked Nucleic Acid Oligonucleotides for siRNA Preclinical Bioanalytics
Despite the exquisite potential of siRNA as a therapeutic, the mechanism(s) responsible for the robust indirect exposure-response relationships have not been fully elucidated. To understand the siRNA properties linked to potent activity, requires the disposition of siRNA to be characterized. A techn...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6401054/ https://ncbi.nlm.nih.gov/pubmed/30837588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40187-4 |
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