Rapid Downregulation of DAB2 by Toll-Like Receptor Activation Contributes to a Pro-Inflammatory Switch in Activated Dendritic Cells

Dendritic cells (DCs) are pivotal in regulating tolerogenic as well as immunogenic responses against microorganisms by directing both the innate and adaptive immune response. In health, phenotypically different DC subsets found in the gut mucosa are maintained in their tolerogenic state but switch t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Figliuolo da Paz, Vanessa, Jamwal, Deepa R., Gurney, Michael, Midura-Kiela, Monica, Harrison, Christy A., Cox, Christopher, Wilson, Jean M., Ghishan, Fayez K., Kiela, Pawel R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400992/
https://ncbi.nlm.nih.gov/pubmed/30873168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00304
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