Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson’s Disease and Dementia with Lewy Bodies

Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). The present study aims to gain more insight into changes in lysosomal activity in different brain re...

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Библиографические подробности
Опубликовано в: :Mol Neurobiol
Главные авторы: Moors, Tim E., Paciotti, Silvia, Ingrassia, Angela, Quadri, Marialuisa, Breedveld, Guido, Tasegian, Anna, Chiasserini, Davide, Eusebi, Paolo, Duran-Pacheco, Gonzalo, Kremer, Thomas, Calabresi, Paolo, Bonifati, Vincenzo, Parnetti, Lucilla, Beccari, Tommaso, van de Berg, Wilma D. J.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400877/
https://ncbi.nlm.nih.gov/pubmed/29948939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1090-0
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