Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson’s Disease and Dementia with Lewy Bodies

Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). The present study aims to gain more insight into changes in lysosomal activity in different brain re...

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Publicat a:Mol Neurobiol
Autors principals: Moors, Tim E., Paciotti, Silvia, Ingrassia, Angela, Quadri, Marialuisa, Breedveld, Guido, Tasegian, Anna, Chiasserini, Davide, Eusebi, Paolo, Duran-Pacheco, Gonzalo, Kremer, Thomas, Calabresi, Paolo, Bonifati, Vincenzo, Parnetti, Lucilla, Beccari, Tommaso, van de Berg, Wilma D. J.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400877/
https://ncbi.nlm.nih.gov/pubmed/29948939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1090-0
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