Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson’s Disease and Dementia with Lewy Bodies

Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). The present study aims to gain more insight into changes in lysosomal activity in different brain re...

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Pubblicato in:Mol Neurobiol
Autori principali: Moors, Tim E., Paciotti, Silvia, Ingrassia, Angela, Quadri, Marialuisa, Breedveld, Guido, Tasegian, Anna, Chiasserini, Davide, Eusebi, Paolo, Duran-Pacheco, Gonzalo, Kremer, Thomas, Calabresi, Paolo, Bonifati, Vincenzo, Parnetti, Lucilla, Beccari, Tommaso, van de Berg, Wilma D. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400877/
https://ncbi.nlm.nih.gov/pubmed/29948939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1090-0
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