Pseudomonas aeruginosa Exoprotein-Induced Barrier Disruption Correlates With Elastase Activity and Marks Chronic Rhinosinusitis Severity

Background: Pseudomonas aeruginosa causes severe chronic respiratory diseases and is associated with recalcitrant chronic rhinosinusitis (CRS). P. aeruginosa exoproteins contain virulence factors and play important roles in the pathogenicity of P. aeruginosa, however their role in CRS pathophysiolog...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Li, Jian, Ramezanpour, Mahnaz, Fong, Stephanie A., Cooksley, Clare, Murphy, Jae, Suzuki, Masanobu, Psaltis, Alkis J., Wormald, Peter John, Vreugde, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Cellular and Infection Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400838/
https://ncbi.nlm.nih.gov/pubmed/30873390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00038
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