Pseudomonas aeruginosa Exoprotein-Induced Barrier Disruption Correlates With Elastase Activity and Marks Chronic Rhinosinusitis Severity

Background: Pseudomonas aeruginosa causes severe chronic respiratory diseases and is associated with recalcitrant chronic rhinosinusitis (CRS). P. aeruginosa exoproteins contain virulence factors and play important roles in the pathogenicity of P. aeruginosa, however their role in CRS pathophysiolog...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Li, Jian, Ramezanpour, Mahnaz, Fong, Stephanie A., Cooksley, Clare, Murphy, Jae, Suzuki, Masanobu, Psaltis, Alkis J., Wormald, Peter John, Vreugde, Sarah
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Cellular and Infection Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400838/
https://ncbi.nlm.nih.gov/pubmed/30873390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00038
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