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Pseudomonas aeruginosa Exoprotein-Induced Barrier Disruption Correlates With Elastase Activity and Marks Chronic Rhinosinusitis Severity

Background: Pseudomonas aeruginosa causes severe chronic respiratory diseases and is associated with recalcitrant chronic rhinosinusitis (CRS). P. aeruginosa exoproteins contain virulence factors and play important roles in the pathogenicity of P. aeruginosa, however their role in CRS pathophysiolog...

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Détails bibliographiques
Publié dans:Front Cell Infect Microbiol
Auteurs principaux: Li, Jian, Ramezanpour, Mahnaz, Fong, Stephanie A., Cooksley, Clare, Murphy, Jae, Suzuki, Masanobu, Psaltis, Alkis J., Wormald, Peter John, Vreugde, Sarah
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400838/
https://ncbi.nlm.nih.gov/pubmed/30873390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00038
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