Pseudomonas aeruginosa Exoprotein-Induced Barrier Disruption Correlates With Elastase Activity and Marks Chronic Rhinosinusitis Severity

Background: Pseudomonas aeruginosa causes severe chronic respiratory diseases and is associated with recalcitrant chronic rhinosinusitis (CRS). P. aeruginosa exoproteins contain virulence factors and play important roles in the pathogenicity of P. aeruginosa, however their role in CRS pathophysiolog...

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Bibliografiske detaljer
Udgivet i:Front Cell Infect Microbiol
Main Authors: Li, Jian, Ramezanpour, Mahnaz, Fong, Stephanie A., Cooksley, Clare, Murphy, Jae, Suzuki, Masanobu, Psaltis, Alkis J., Wormald, Peter John, Vreugde, Sarah
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Cellular and Infection Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400838/
https://ncbi.nlm.nih.gov/pubmed/30873390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00038
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