Downregulation of PDK4 Increases Lipogenesis and Associates with Poor Prognosis in Hepatocellular Carcinoma

Alterations in cellular metabolism are one of the characteristics in cancer. They are not only the result of tumor progression but also the cause of cancer initiation. Pyruvate dehydrogenase kinase 4 (PDK4) is a key metabolic enzyme, which regulates cell metabolism by inhibiting pyruvate dehydrogena...

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Dettagli Bibliografici
Pubblicato in:J Cancer
Autori principali: Yang, Chen, Wang, Siying, Ruan, Haoyu, Li, Botai, Cheng, Zhuoan, He, Jia, Zuo, Qiaozhu, Yu, Chengtao, Wang, Hui, Lv, Yuanyuan, Gu, Dishui, Jin, Guangzhi, Yao, Ming, Qin, Wenxin, Jin, Haojie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2019
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400816/
https://ncbi.nlm.nih.gov/pubmed/30854098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.27226
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