Downregulation of PDK4 Increases Lipogenesis and Associates with Poor Prognosis in Hepatocellular Carcinoma

Alterations in cellular metabolism are one of the characteristics in cancer. They are not only the result of tumor progression but also the cause of cancer initiation. Pyruvate dehydrogenase kinase 4 (PDK4) is a key metabolic enzyme, which regulates cell metabolism by inhibiting pyruvate dehydrogena...

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Опубликовано в: :J Cancer
Главные авторы: Yang, Chen, Wang, Siying, Ruan, Haoyu, Li, Botai, Cheng, Zhuoan, He, Jia, Zuo, Qiaozhu, Yu, Chengtao, Wang, Hui, Lv, Yuanyuan, Gu, Dishui, Jin, Guangzhi, Yao, Ming, Qin, Wenxin, Jin, Haojie
Формат: Artigo
Язык:Inglês
Опубликовано: Ivyspring International Publisher 2019
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400816/
https://ncbi.nlm.nih.gov/pubmed/30854098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.27226
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