Downregulation of PDK4 Increases Lipogenesis and Associates with Poor Prognosis in Hepatocellular Carcinoma

Alterations in cellular metabolism are one of the characteristics in cancer. They are not only the result of tumor progression but also the cause of cancer initiation. Pyruvate dehydrogenase kinase 4 (PDK4) is a key metabolic enzyme, which regulates cell metabolism by inhibiting pyruvate dehydrogena...

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Bibliografische gegevens
Gepubliceerd in:J Cancer
Hoofdauteurs: Yang, Chen, Wang, Siying, Ruan, Haoyu, Li, Botai, Cheng, Zhuoan, He, Jia, Zuo, Qiaozhu, Yu, Chengtao, Wang, Hui, Lv, Yuanyuan, Gu, Dishui, Jin, Guangzhi, Yao, Ming, Qin, Wenxin, Jin, Haojie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2019
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400816/
https://ncbi.nlm.nih.gov/pubmed/30854098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.27226
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