Downregulation of PDK4 Increases Lipogenesis and Associates with Poor Prognosis in Hepatocellular Carcinoma

Alterations in cellular metabolism are one of the characteristics in cancer. They are not only the result of tumor progression but also the cause of cancer initiation. Pyruvate dehydrogenase kinase 4 (PDK4) is a key metabolic enzyme, which regulates cell metabolism by inhibiting pyruvate dehydrogena...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Yang, Chen, Wang, Siying, Ruan, Haoyu, Li, Botai, Cheng, Zhuoan, He, Jia, Zuo, Qiaozhu, Yu, Chengtao, Wang, Hui, Lv, Yuanyuan, Gu, Dishui, Jin, Guangzhi, Yao, Ming, Qin, Wenxin, Jin, Haojie
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400816/
https://ncbi.nlm.nih.gov/pubmed/30854098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.27226
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