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Cryo-EM of retinoschisin branched networks suggests an intercellular adhesive scaffold in the retina
Mutations in the retinal protein retinoschisin (RS1) cause progressive loss of vision in young males, a form of macular degeneration called X-linked retinoschisis (XLRS). We previously solved the structure of RS1, a 16-mer composed of paired back-to-back octameric rings. Here, we show by cryo–electr...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400569/ https://ncbi.nlm.nih.gov/pubmed/30630865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201806148 |
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