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Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner
Chronic viral infections are widespread among humans, with ∼8–12 chronic viral infections per individual, and there is epidemiological proof that these impair heterologous immunity. We studied the impact of chronic LCMV infection on the phenotype and function of memory bystander CD8(+) T cells. Acti...
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| Veröffentlicht in: | J Exp Med |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400541/ https://ncbi.nlm.nih.gov/pubmed/30745322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181589 |
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