Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner

Chronic viral infections are widespread among humans, with ∼8–12 chronic viral infections per individual, and there is epidemiological proof that these impair heterologous immunity. We studied the impact of chronic LCMV infection on the phenotype and function of memory bystander CD8(+) T cells. Acti...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Barnstorf, Isabel, Borsa, Mariana, Baumann, Nicolas, Pallmer, Katharina, Yermanos, Alexander, Joller, Nicole, Spörri, Roman, Welten, Suzanne P.M., Kräutler, Nike J., Oxenius, Annette
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400541/
https://ncbi.nlm.nih.gov/pubmed/30745322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181589
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