Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner

Chronic viral infections are widespread among humans, with ∼8–12 chronic viral infections per individual, and there is epidemiological proof that these impair heterologous immunity. We studied the impact of chronic LCMV infection on the phenotype and function of memory bystander CD8(+) T cells. Acti...

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Publicado en:J Exp Med
Autores principales: Barnstorf, Isabel, Borsa, Mariana, Baumann, Nicolas, Pallmer, Katharina, Yermanos, Alexander, Joller, Nicole, Spörri, Roman, Welten, Suzanne P.M., Kräutler, Nike J., Oxenius, Annette
Formato: Artigo
Lenguaje:Inglês
Publicado: Rockefeller University Press 2019
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400541/
https://ncbi.nlm.nih.gov/pubmed/30745322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181589
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