Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner

Chronic viral infections are widespread among humans, with ∼8–12 chronic viral infections per individual, and there is epidemiological proof that these impair heterologous immunity. We studied the impact of chronic LCMV infection on the phenotype and function of memory bystander CD8(+) T cells. Acti...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Barnstorf, Isabel, Borsa, Mariana, Baumann, Nicolas, Pallmer, Katharina, Yermanos, Alexander, Joller, Nicole, Spörri, Roman, Welten, Suzanne P.M., Kräutler, Nike J., Oxenius, Annette
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400541/
https://ncbi.nlm.nih.gov/pubmed/30745322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181589
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