Interferon-induced guanylate-binding proteins: Guardians of host defense in health and disease

Guanylate-binding proteins (GBPs) have recently emerged as central orchestrators of immunity to infection, inflammation, and neoplastic diseases. Within numerous host cell types, these IFN-induced GTPases assemble into large nanomachines that execute distinct host defense activities against a wide v...

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Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Tretina, Kyle, Park, Eui-Soon, Maminska, Agnieszka, MacMicking, John D.
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400534/
https://ncbi.nlm.nih.gov/pubmed/30755454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182031
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