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Interferon-inducible effector mechanisms in cell-autonomous immunity

Interferons (IFNs) induce the expression of hundreds of genes as part of an elaborate antimicrobial programme designed to combat infection in all nucleated cells — a process termed cell-autonomous immunity. As described in this Review, recent genomic and subgenomic analyses have begun to assign func...

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Bibliographic Details
Main Author: MacMicking, John D.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150610/
https://ncbi.nlm.nih.gov/pubmed/22531325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3210
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