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Cell-autonomous immunity by IFN-induced GBPs in animals and plants

Inside host cells, guanylate binding proteins (GBPs) rapidly assemble into large antimicrobial defense complexes that combat a wide variety of bacterial pathogens. These massive nanomachines often completely coat targeted microbes where they act as recruitment platforms for downstream effectors capa...

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Bibliographic Details
Published in:Curr Opin Immunol
Main Authors: Huang, Shuai, Meng, Qingcai, Maminska, Agnieszka, MacMicking, John D
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800610/
https://ncbi.nlm.nih.gov/pubmed/31176142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2019.04.017
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