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miR-7977 inhibits the Hippo-YAP signaling pathway in bone marrow mesenchymal stromal cells

We and others have demonstrated that various abnormalities of the bone marrow (BM) mesenchymal stromal cells (MSCs) such as aberrant cytokine expression, abnormal hedgehog signaling, and impaired miRNA biogenesis are observed in patients with acute myeloid leukemia (AML). However, underlying mechani...

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Veröffentlicht in:PLoS One
Hauptverfasser: Yoshida, Masahiro, Horiguchi, Hiroto, Kikuchi, Shohei, Iyama, Satoshi, Ikeda, Hiroshi, Goto, Akari, Kawano, Yutaka, Murase, Kazuyuki, Takada, Kohichi, Miyanishi, Koji, Kato, Junji, Kobune, Masayoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400381/
https://ncbi.nlm.nih.gov/pubmed/30835743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213220
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