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Extracellular vesicle miR-7977 is involved in hematopoietic dysfunction of mesenchymal stromal cells via poly(rC) binding protein 1 reduction in myeloid neoplasms

The failure of normal hematopoiesis is observed in myeloid neoplasms. However, the precise mechanisms governing the replacement of normal hematopoietic stem cells in their niche by myeloid neoplasm stem cells have not yet been clarified. Primary acute myeloid leukemia and myelodysplastic syndrome ce...

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Vydáno v:Haematologica
Hlavní autoři: Horiguchi, Hiroto, Kobune, Masayoshi, Kikuchi, Shohei, Yoshida, Masahiro, Murata, Masaki, Murase, Kazuyuki, Iyama, Satoshi, Takada, Kohichi, Sato, Tsutomu, Ono, Kaoru, Hashimoto, Akari, Tatekoshi, Ayumi, Kamihara, Yusuke, Kawano, Yutaka, Miyanishi, Koji, Sawada, Norimasa, Kato, Junji
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004399/
https://ncbi.nlm.nih.gov/pubmed/26802051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.134932
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