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Inflammation NODs to Antagonists of RIP2-XIAP Interaction

While innate immunity is crucial for host defense, dysregulated signaling activation leads to pathological inflammation. In this issue of Molecular Cell, Goncharov et al. (2018) present a strategy to combat inflamma-tory diseases by disrupting RIP2-XIAP interaction in NOD2-mediated signaling.

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Bibliografische gegevens
Gepubliceerd in:Mol Cell
Hoofdauteurs: Xia, Shiyu, Fu, Tian-Min, Wu, Hao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400283/
https://ncbi.nlm.nih.gov/pubmed/29452633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.02.003
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