Knockout of alpha 5 nicotinic acetylcholine receptors subunit alters ethanol-mediated behavioral effects and reward in mice.

Evidence suggests that there is an association between polymorphisms in the α5 nicotinic acetylcholine receptor (nAChR) subunit and risk of developing alcohol dependence in humans. The α5 nAChR subunit has also recently been shown to modulate some of the acute response to ethanol in mice. The aim of...

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Publicado en:Neuropharmacology
Autores principales: Dawson, Anton, Wolstenholme, Jennifer T., Roni, Monzurul A., Campbell, Vera C., Jackson, Asti, Slater, Cassandra, Bagdas, Deniz, Perez, Erika E., Bettinger, Jill C., De Biasi, Mariella, Miles, Michael F., Damaj, M. Imad
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400055/
https://ncbi.nlm.nih.gov/pubmed/29944862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.06.031
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