ロード中...
Exploring the Role of the Third Active Site Metal Ion in DNA Polymerase η with QM/MM Free Energy Simulations
The enzyme human DNA polymerase η (Pol η) is critical for bypassing lesions during DNA replication. In addition to the two Mg(2+) ions aligning the active site, experiments suggest that a third Mg(2+) ion could play an essential catalytic role. Herein the role of this third metal ion is investigated...
保存先:
| 出版年: | J Am Chem Soc |
|---|---|
| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6399739/ https://ncbi.nlm.nih.gov/pubmed/29932331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b05177 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|