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Acid sphingomyelinase deficiency protects mitochondria and improves function recovery after brain injury

Traumatic brain injury (TBI) is one of the leading causes of disability worldwide and a prominent risk factor for neurodegenerative diseases. The expansion of nervous tissue damage after the initial trauma involves a multifactorial cascade of events, including excitotoxicity, oxidative stress, infla...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Novgorodov, Sergei A., Voltin, Joshua R., Wang, Wenxue, Tomlinson, Stephen, Riley, Christopher L., Gudz, Tatyana I.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399498/
https://ncbi.nlm.nih.gov/pubmed/30662008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M091132
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