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A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha
The minor phospholipid, phosphatidylinositol 4-phosphate (PI4P), is emerging as a key regulator of lipid transfer in ER-membrane contact sites. Four different phosphatidylinositol 4-kinase (PI4K) enzymes generate PI4P in different membrane compartments supporting distinct cellular processes, many of...
שמור ב:
| הוצא לאור ב: | J Lipid Res |
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| Main Authors: | , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The American Society for Biochemistry and Molecular Biology
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6399489/ https://ncbi.nlm.nih.gov/pubmed/30626625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D090159 |
| תגים: |
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