Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses

Remdesivir was shown to inhibit RNA-dependent RNA-polymerases (RdRp) from distinct viral families such as from Filoviridae (Ebola) and Coronaviridae (SARS-CoV, SARS-CoV-2, MERS). In this study, we tested the ability of remdesivir to inhibit RdRps from the Flaviviridae family. Instead of remdesivir,...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Konkolova, Eva, Dejmek, Milan, Hřebabecký, Hubert, Šála, Michal, Böserle, Jiří, Nencka, Radim, Boura, Evzen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2020
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403104/
https://ncbi.nlm.nih.gov/pubmed/32763313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2020.104899
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