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Structural analysis of the putative SARS-CoV-2 primase complex
We report the crystal structure of the SARS-CoV-2 putative primase composed of the nsp7 and nsp8 proteins. We observed a dimer of dimers (2:2 nsp7-nsp8) in the crystallographic asymmetric unit. The structure revealed a fold with a helical core of the heterotetramer formed by both nsp7 and nsp8 that...
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| Publicado en: | J Struct Biol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier Inc.
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7289108/ https://ncbi.nlm.nih.gov/pubmed/32535228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2020.107548 |
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