Shorter TCR β-Chains Are Highly Enriched During Thymic Selection and Antigen-Driven Selection

The adaptive immune system uses several strategies to generate a repertoire of T cell receptors (TCR) with sufficient diversity to recognize the universe of potential pathogens. However, it remains unclear how differences in the T cell receptor (TCR) contribute to heterogeneity in T cell state. In t...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Hou, Xianliang, Zeng, Ping, Zhang, Xujun, Chen, Jianing, Liang, Yan, Yang, Jiezuan, Yang, Yida, Liu, Xiangdong, Diao, Hongyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399399/
https://ncbi.nlm.nih.gov/pubmed/30863407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00299
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