Inhibition of lymphatic proliferation by the selective VEGFR-3 inhibitor SAR131675 ameliorates diabetic nephropathy in db/db mice

Recent studies have demonstrated that chronic inflammation-induced lymphangiogenesis plays a crucial role in the progression of various renal diseases, including diabetic nephropathy. SAR131675 is a selective vascular endothelial cell growth factor receptor-3 (VEGFR-3)-tyrosine kinase inhibitor that...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Hwang, Seun Deuk, Song, Joon Ho, Kim, Yaeni, Lim, Ji Hee, Kim, Min Young, Kim, Eun Nim, Hong, Yu Ah, Chung, Sungjin, Choi, Bum Soon, Kim, Yong-Soo, Park, Cheol Whee
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399322/
https://ncbi.nlm.nih.gov/pubmed/30833548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1436-1
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