Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy

Apoptosis and autophagy are harmoniously regulated biological processes for maintaining tissue homeostasis. AMP-activated protein kinase (AMPK) functions as a metabolic sensor to coordinate cellular survival and function in various organs, including the kidney. We investigated the renoprotective eff...

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Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Lim, Ji Hee, Kim, Hyung Wook, Kim, Min Young, Kim, Tae Woo, Kim, Eun Nim, Kim, Yaeni, Chung, Sungjin, Kim, Young Soo, Choi, Bum Soon, Kim, Yong-Soo, Chang, Yoon Sik, Kim, Hye Won, Park, Cheol Whee
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833853/
https://ncbi.nlm.nih.gov/pubmed/29449563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0324-4
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