The Adiponectin Receptor Agonist AdipoRon Ameliorates Diabetic Nephropathy in a Model of Type 2 Diabetes

Adiponectin exerts renoprotective effects against diabetic nephropathy (DN) by activating the AMP-activated protein kinase (AMPK)/peroxisome proliferative-activated receptor–α (PPARα) pathway through adiponectin receptors (AdipoRs). AdipoRon is an orally active synthetic adiponectin receptor agonist...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Kim, Yaeni, Lim, Ji Hee, Kim, Min Young, Kim, Eun Nim, Yoon, Hye Eun, Shin, Seok Joon, Choi, Bum Soon, Kim, Yong-Soo, Chang, Yoon Sik, Park, Cheol Whee
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2018
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875945/
https://ncbi.nlm.nih.gov/pubmed/29330340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017060627
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