Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model

Bicalutamide (Bic) is frequently used in androgen deprivation therapy (ADT) for treating prostate cancer. ADT-induced hypogonadism was reported to have the potential to lead to acute kidney injury (AKI). ADT was also shown to induce bladder fibrosis via induction of the transforming growth factor (T...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Peng, Chiung Chi, Chen, Chang-Yu, Chen, Chang-Rong, Chen, Chang-Jui, Shen, Kun-Hung, Chen, Kuan-Chou, Peng, Robert Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399217/
https://ncbi.nlm.nih.gov/pubmed/30833616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39533-3
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