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Blocking α(2)δ-1 Subunit Reduces Bladder Hypersensitivity and Inflammation in a Cystitis Mouse Model by Decreasing NF-kB Pathway Activation
Bladder pain is frequently associated with bladder inflammation, as in conditions like interstitial cystitis (IC), for which current analgesic therapies have limited efficacy. The antinociceptive effect of alpha-2-delta (α(2)δ) ligands on inflammation-associated visceral pain like that experienced i...
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| 出版年: | Front Pharmacol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6399165/ https://ncbi.nlm.nih.gov/pubmed/30863309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00133 |
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