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A Bayesian design for phase I cancer therapeutic vaccine trials
Phase I clinical trials are the first step in drug development to test a new drug or drug combination on humans. Typical designs of Phase I trials use toxicity as the primary endpoint and aim to find the maximum tolerable dosage. However, these designs are poorly applicable for the development of ca...
Gardado en:
| Publicado en: | Stat Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6399043/ https://ncbi.nlm.nih.gov/pubmed/30368868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8021 |
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