Path‐seq identifies an essential mycolate remodeling program for mycobacterial host adaptation

The success of Mycobacterium tuberculosis (MTB) stems from its ability to remain hidden from the immune system within macrophages. Here, we report a new technology (Path‐seq) to sequence miniscule amounts of MTB transcripts within up to million‐fold excess host RNA. Using Path‐seq and regulatory net...

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Dettagli Bibliografici
Pubblicato in:Mol Syst Biol
Autori principali: Peterson, Eliza JR, Bailo, Rebeca, Rothchild, Alissa C, Arrieta‐Ortiz, Mario L, Kaur, Amardeep, Pan, Min, Mai, Dat, Abidi, Abrar A, Cooper, Charlotte, Aderem, Alan, Bhatt, Apoorva, Baliga, Nitin S
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398593/
https://ncbi.nlm.nih.gov/pubmed/30833303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20188584
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